Clinical Scientist - Randox Laboratories : Job Details

Clinical Scientist - NGS (24/LINI)

Randox Clinical Laboratory Services [Genomics Services Group] require an experienced Clinical Scientist to work with the existing team developing new NGS tests and reporting genomic test results. The person must be registered with HCPC [Health and Care Professions Council UK] as a Clinical Scientist. The main purpose of this post is to assist in development of new tests, production of automated reporting systems and to prepare clinical interpretative reports when required. In addition, the person will be expected to provide expert genetic and genomics advice to sales and marketing teams and staff at the Randox Health Clinics.

The current genomic tests offered are:

• Hereditary Cancer genes panel [94 genes] - including an HBOC panel
• Hereditary Cardiac genes panel [174 genes] - including a Familial Hypercholesterolaemia panel

NGS panels in development:

• Human Exomes
• Human Genomes
• Pharmacogenomics
• Nutrigenomics and Lifestyle
• Metagenomics

Randox has a large genomic sequencing facility at the Randox Clinical Laboratory Services unit at the Randox Science Park in Antrim, UK. This laboratory has an Illumina NovaSeq 6000, NextSeq 2000 and MiSeq sequencers, Tecan Evo robotics with accessory equipment such as thermal cyclers, Tape stations, SeqStudio Genetic analyser. The facility also has an iScan high density array equipment. The unit has ~30 staff including senior clinical scientist, laboratory managers, team leaders, NGS scientists, and a bioinformatics team.

There are options for full time, part-time flexible working and the Clinical Scientist can be based in the Randox Science Park, Antrim UK or at one of the Randox Health Clinics in London or other sites across the UK. Alternatively remote working from home will be considered with regular visits to the Randox Science Park, Antrim for training and review meetings.

Salary will be based on previous experience and qualifications.

The Role:

• To ensure strict adherence to all laboratory procedures
• To ensure that all work is done in compliance with ISO 17025 / 15189 or CAP requirements
• To ensure that all assays meet the specified QC parameters for DNA extraction, during NGS library preparation, NGS sequencing and data analysis
• To assist in the development of new molecular genetic assays
• DNA sequencing including NGS
• Use of Bioinformatics packages and variant interpretation software
• Implement clinical diagnostic reporting procedures for NGS assays and other genetic assays
• To apply a systematic approach for the analysis of DNA sequence data and for the interpretation of variants
• Deliver presentations on NGS diagnostic tests as required

Skills and Experience:

Essential:

• Qualified to Honours degree level in Molecular Genetics, Biomedical Sciences, Molecular Biology, Biochemistry, Microbiology or a Life Science discipline with a 2:1 grade or above
• To be registered with HCPC as a Clinical Scientist in molecular genetics or related discipline involving molecular biology
• To maintain professional membership of national and international societies such as ACGS, RCPath etc.
• Experience in Molecular Diagnostic Testing, sequence variant interpretation and clinical reporting
• 3 years’ experience in a clinical diagnostic laboratory or equivalent
• Excellent presentation and communication skills
• Must have excellent time management, organisational and database skills (Proficient in Microsoft Windows and Office packages)
• Ability to work independently

Desirable

• Further qualification MSc or PhD in relevant discipline related to molecular genetics
• Experience in clinical interpretative reporting of NGS panel tests for inherited cancer and / or inherited cardiac disorders, clinical exomes or genomes, viral genomes.
• Experience in Bioinformatics packages and sequence variant interpretation.

This is a unique opportunity to join an innovative international company in a growing industry that can provide career security and genuine advancement opportunities for those who show potential.

About Randox:

An international company operating in over 145 countries that continues to have unparalleled growth, Randox Laboratories has been the heartbeat of the UK’s National COVID Testing Programme throughout the pandemic. In early 2020 Randox recognised the threat from COVID-19 and, based on over 40 years of diagnostic experience, quickly developed a test to accurately identify the virus. Testing at scale commenced within weeks to support the UK’s National Testing Programme and private clients alike. Through the enormous effort and commitment of its staff Randox is currently operating at a capacity of 180,000 COVID-19 samples per day, making it the most productive laboratory in the UK and Ireland and amongst the very largest in Europe.

Additionally, as a world leader in diagnostics for clinical healthcare, toxicology and food security, our expertise and product portfolio have assisted laboratories across the world in improving health and saving lives. Our global success is a result of our pioneering products and the commitment & skill of our workforce, which continue to grow exponentially.

Central to the Randox ethos is our drive and determination to improve healthcare worldwide and every one of our talented staff play a role in this. In order to serve our growing international markets, we require high calibre applicants with scientific, engineering, software and broader business skills - including sales, marketing, logistics, finance and many more. Join the Randox team and play your part in improving the health of millions.

Randox Laboratories Limited is an Equal Opportunities Employer.