Senior/Associate Principal Scientist, siRNA Project Lead - Hansoh Bio : Job Details

Hansoh Bio

A U.S.-based research & development subsidiary of Hansoh Pharma, Hansoh Bio is a biotech devoted to discovering and developing breakthrough therapies that conquer serious diseases and disorders for patients around the world. Hansoh Pharma is a leading biopharmaceutical company in Asia. Founded in 1995, we are committed to discovering and developing life-changing medicines to help patients. Our rapidly growing workforce of 9,000+ employees, and our fully integrated research and development, manufacturing and commercial capabilities have propelled us into leadership positions across a broad range of therapeutic areas, including CNS, oncology, infectious disease, and metabolic disorders. With 1,400 professionals across multiple R&D functions, we rank 2nd in innovation among all Chinese biotech and pharmaceutical companies, based on new molecular entities developed for clinical development. Since an IPO on Hong Kong stock exchange in June 2019, we have raised $1.6B from global top-tier institutional investors; with a current equity value of approximately $27B, Hansoh is the 2nd largest biopharmaceutical companies in China and 6th largest in Asia by market capitalization. For more information, please visit www.hspharm.com.

The Position Senior/Associate Principal Scientist

At Hansoh, we never rest in the quest of bringing truly life-changing treatments to patients. Beyond small molecules and biotherapeutics, Hansoh is extending its influence on other modalities such as siRNA. We are seeking a motivated, resourceful, and collaborative Senior/Associate Principal Scientist to contribute to our company's siRNA drug discovery and early clinical development efforts. The ideal candidate will lead multiple projects at different stages as a siRNA team representative, regularly interacting with discovery and downstream teams and SMEs from other functions. This role offers tremendous growth opportunity within a dynamic and science-driven organization

Responsibilities

Work collaboratively with cross-functional teams to manage the development of siRNA projects from lead candidate selection to IND-enabling preclinical studies. Build the project execution plan in line with strategic priorities.

Oversee internal and external efforts to evaluate the lead candidates in cellular and animal models. Serve as the primary contact to manage, guide, and execute studies in CROs, ensuring studies are completed to meet program objectives, timeline, and quality requirements.

Prepare and organize data for presentation. Communicates strategy and results in written and oral reports to various levels of management.

Contribute to the preparation/editing/review of documents for regulatory submission.

Maintain a current appreciation of scientific literature and understanding of the state of the art in oligonucleotide therapeutics. Provides expert input in evaluation of external/partnership opportunities.

Key Qualifications

Ph.D./Pharm.D. in biochemistry, pharmacology, pharmaceutical sciences, or a related field with 5+ years of experience in drug discovery and/or development.

Thorough knowledge of working with oligonucleotide therapeutics.

Experience working as a project lead to advance discovery projects to the development stage. Demonstrated experience successfully prioritizing and managing projects and timelines. Ability to independently translate strategy into action in a timely manner.

Strong presentation skills. Effective communication and interpersonal skills.

Preferred Experience and Skills

Experience working within a research-driven Biotech and/or pharmaceutical industry experience is desirable.

Independent thinking, effectively working in highly matrixed team setting and ability to multi-task in a fast-paced environment. Desire to learn and tackle new challenges and initiatives.

In-depth understanding of the PK, pharmacology, and ADME aspects specific to oligonucleotide-based therapeutics is a plus.

Prior experience with regulatory submission is a plus.

Knowledge and experience with cardiometabolic diseases is desirable.

Company providescompetitive compensation withhealth, dental and vision coverage, as well as a matching401K retirement plan.

HansohBio is an Equal Opportunity Employer. Hansoh doesnot discriminate on the basisof race, religion, color, sex, gender identity, sexual orientation, age, national origin,veteran status, or any otherstatus protected underfederal, state, or local law.