Scientific Associate Director - PKDM (Small Molecule ADME) - Amgen : Job Details

Your core responsibilities include:Serving as a subject matter expert of small molecule biotransformation and leading biotransformation activities to support the programs and develop strategies to reduce/mitigate risks due to metabolism. Leveraging current biotransformation knowledge of metabolism as well as developing/implementing novel tools to efficiently support biotransformation related activities. Serving as a functional PKDM project team representative (PTR) and subject matter expert on the ADME/ PK of small molecule therapeutics, collaborating with scientists across our PKDM scientific community. Leveraging specialized ADME/ PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK/ PD, or physiologically-based pharmacokinetic modeling (PBPK) to impact project progression and decision-making. Planning and executing mechanistic ADME/ PK analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics to...Director, Associate, Sales Representative, Business Services, Skills