Research Associate, Infectious Disease (Arias Group - Biohub SF) - Chan Zuckerberg Biohub - San Francisco : Job Details

The Chan Zuckerberg Biohub San Francisco (CZ Biohub SF) is an independent nonprofit research institute that brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. CZ Biohub SF itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at CZ Biohub San Francisco facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The Arias Group at the Chan Zuckerberg Biohub is looking for a curious, energetic, passionate, and talented Research Associate to join us. We are interested in exploring the mechanisms used by viruses to hijack the protein synthesis machinery. Our ultimate goal is to identify factors required for viral replication but dispensable for normal cell function that could be exploited to develop new antiviral strategies. Our primary research will evaluate the antiviral target potential of previously identified factors and establish methods to identify new candidate targets, including CRISPR-based screens and Ribosome Profiling.

You will

• Under the mentorship and supervision of senior researchers, plan and carry out experiments designed to understand host and virus dynamics during an infection
• Create and maintain a library of cell lines as needed for various studies
• Learn and utilize cutting edge techniques involving microscopy, flow cytometry, mass spectrometry, CRISPR, drug screens and high throughput sequencing
• Work with personnel from different research platforms (proteomics, genomics, imaging, cell biology, data science)
• Troubleshoot protocols, maintain detailed records, analyze results, and contribute ideas to research projects

You have

• Bachelor's degree in a life science or associated field with relevant coursework including molecular biology, cell biology, biochemistry and microbiology/virology
• Minimum of 1 year of experience with wet laboratory techniques (DNA and RNA isolation, PCR, cloning/construct design)
• Hands on tissue culture experience
• Familiarity with gene manipulation and expression analysis methods (gene overexpression and stable expression, RNAi, CRISPR, qPCR, sequencing)
• Familiarity with protein tagging, expression and purification processes
• Experience in data collection, analysis, and interpretation
• Attention to detail and very strong organizational skills
• Excellent written and verbal communication skills
• Ability to multi-task and work both independently and collaboratively across platforms

Nice to have –

• Master's degree in life sciences or related field
• Experience working with viruses
• Previous research, job or internship experience in an academic or industry setting involving one year of tissue culture experience.
• Experience with proteomics and transcriptomics
• Experience with drug screens

Compensation

The San Francisco, CA base pay range for this role is Research Associate I = $52,000.00 - $77,000.00 and Research Associate II = $67,000.00 - $99,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

What We Provide

• Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
• A collegial and collaborative environment consisting of diverse expertise
• Access to collaborators, resources and facilities at our three partner universities (Stanford University, UC Berkeley, and UC San Francisco) and at partner organizations in the SF Bay Area and beyond
• Competitive compensation and benefits commensurate with the experience

If you're interested in a role but your previous experience doesn't perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Pursuant to the California Fair Chance Act, we will consider for employment qualified applicants with arrest and conviction records.