Postdoc Computational – Koo Lab - The University of Texas MD Anderson Cancer Center : Job Details

Job Title: Postdoc Computational – Koo Lab

Job Number: 90599

Location: Cold Spring Harbor, US

Job Description

Position Description

The Koo Lab at the Simons Center for Quantitative Biology (SCQB) at Cold Spring Harbor Laboratory (CSHL) is seeking a highly motivated and self-directed postdoctoral fellow to work at the intersection of machine learning and genomics.

This position focuses on developing large language models (LLMs) and diffusion models to study gene regulation using high-throughput functional genomics data. The work will emphasize applying state-of-the-art machine learning techniques to uncover the mechanisms of cis-regulatory elements and sequence motifs that coordinate gene expression.

Key Features of the SCQB:

The SCQB is building a cutting-edge experimental core dedicated to generating large-scale perturbation datasets for training and validating ML models. This integration of experimental and computational efforts ensures the maximum impact of research by directly linking model development to high-quality data.

Position Responsibilities:

Position Requirements:

Environment:

Cold Spring Harbor Laboratory is a world-renowned research and educational institution located on Long Island, NY, with easy access to New York City. The Simons Center for Quantitative Biology is a collaborative research environment dedicated to tackling complex biological questions using quantitative approaches. The SCQB's experimental core is a unique initiative that enables tight integration between ML model development and experimental data generation, ensuring models are both robust and biologically validated.

We believe that science is for everyone. We have had researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.

Compensation & Benefits:

Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, paid time off, and a range of recognition and wellness programs. The salary for this role is $76,440.00 per annum. The salary range or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).

CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor

Application Deadline: 2025-06-26