Neuroscience Functional Recording Lead - Kubelt : Job Details

At Eon, we are at the forefront of large-scale neuroscientific connectomic data collection. Our mission is to enable the safe and scalable development of brain emulation technology to empower humanity over the next decade, starting with a digital twin of a mouse.

This is a senior role with substantial responsibility for cell, tissue, and eventually in-vivo mouse recording at Eon. At Eon, we intend to create a large amount of mouse neural recordings and high-resolution connectomic scans to train machine learning models of brain function, and produce structure-to-function translation . The mouse functional recording team lead would lead this functional recording data collection, which would include voltage image (primarily), calcium imaging, and potentially electrophysiological recording or MEA. Extensive, hands-on experience with voltage imaging, and ideally other neural recording modalities is required.

• Protocol Development and Study Design: This responsibility involves creating detailed study protocols that outline the objectives, methodologies, and ethical considerations of neuroscientific experiments on animals.
• Hiring and Team Building: Recruit and build a multidisciplinary team, including mouse surgeons, technicians, and scientists specialized in various recording techniques.
• Lead Functional Imaging Experiments: Oversee and personally execute the first sets of functional recording experiments using advanced techniques such as voltage imaging, calcium imaging or electrophysiology.

• PhD or equivalent qualifications in neuroscience or related field; 3+ years of experience post PhD, or equivalent experience.
• Experience performing voltage/calcium imaging and analysis thereof.
• Machine learning experience would be ideal.
• Experience designing and leading functional imaging experiments, with a track record of generating high-quality data.
• Demonstrated ability to manage and build scientific teams.
• Experience overseeing multiple neuroscientific projects in rodents.

These are examples of projects that you would be working on when joining us:

• Collecting large amounts of voltage imaging datasets, initially cell cultures, then moving to slice and in vivo
• maybe collecting electrophysiology, both using slice recordings and in vivo multi shank electrodes.
• Hiring functional recording team.
• Correlating between functional data and structural data.

• Competitive salary and equity.