Job Location : Pittsburgh,PA, USA
Overview
We are seeking a highly motivated and experienced Head of RNA Production to establish and scale a laboratory dedicated to the production of DNA templates, in vitro–transcribed (IVT) RNA, and lipid nanoparticle–formulated RNA (LNP-RNA). This role combines strategic planning, laboratory build-out, and hands-on process development to enable high-quality nucleic acid production for research and therapeutic applications.
Key Responsibilities
· Implement laboratory workflows for DNA, RNA, and LNP-RNA production and quality assurance.
· Install and maintain critical equipment (purification systems, IVT platforms, TFF, microfluidic LNP systems).
· Develop and execute processes for DNA template generation, RNA synthesis and purification, and LNP formulation.
· Execute and analyze experiments to support continuous process improvement.
· Collaborate with cross-functional partners to ensure seamless process transfer.
· Implement and evaluate QC assays for DNA, RNA, and LNP-RNA (CGE, DLS, etc)
Qualifications
Required:
· PhD in Molecular Biology, Biochemistry, Chemical Engineering, or related field.
· Experience in nucleic acid production, process development, or formulation.
· Strong problem-solving skills and attention to detail.
· Ability to work independently as well as collaboratively in a team environment.
· Excellent communication and organizational skills
· Enthusiastic, responsible, flexible and can handle pressure.
· Experience precisely following Standard Operating Procedures (SOPs)
Preferred:
· Proven track record of establishing or scaling laboratory operations.
· Prior leadership or startup experience, particularly in setting up new capabilities.
· Strong project management skills with ability to balance long-term strategy and day-to-day execution.
Why Join Us?
This is a unique opportunity to collaboratively develop a new lab space and shape the foundation of next-generation RNA and LNP-based technologies and directly impact the growth of an emerging biotech company.