Associate Scientist/Scientist I/Scientist II – Phage Display and Molecular Biology - Work in biotech : Job Details

Associate Scientist/Scientist I/Scientist II – Phage Display and Molecular Biology

This range is provided by Work In Biotech. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$115,000.00/yr - $145,000.00/yr

Role Description:

Our client is seeking an individual with expertise in phage display and molecular biology techniques to help drive their drug discovery programs. We seek an individual that is proficient in designing and executing experiments, has excellent communication and documentation skills, and is excited to expand their skillset in a fast-paced and collaborative research environment. This position will work directly on the development of biotherapeutics for serious diseases, and will be involved in biotherapeutic identification, characterization, optimization, and selection of lead molecules for multiple programs. This is an excellent opportunity to work with a motivated and experienced team and interface directly with multiple research groups, including biotherapeutic discovery, platform engineering, protein sciences, pharmacology, and leadership. The ideal candidate will be an enthusiastic, motivated, and innovative individual who is excited to participate in a dedicated team.

Responsibilities:

• Design and generate naïve antibody/VHH phage display libraries
• Design and generate immune antibody phage display libraries
• Optimize antibody/VHH biophysical and antigen binding properties using phage display
• Phage panning and binder screening for antibody and VHH libraries including ELISA
• Cloning, sequence analysis and clustering, and characterization of antibodies/VHHs selected from phage libraries
• Clearly document results and present at team meetings

Required Skills and Experience:

• BS/MS in Biochemistry or related scientific field, with 4+ years of hands-on experience with phage display and molecular biology
• Extensive experience in phage library panning, including panning strategy design and execution, and binder screening
• Experience with cloning and DNA library design and construction, including naïve and affinity maturation libraries
• Highly collaborative with excellent communication skills
• Ability to work effectively in a fast-paced and cross-functional team environment

Additional Experience Preferred but Not Required:

• Proficiency with PyMOL, MOE, or similar software for protein structure analysis, protein engineering, and library design
• Experience with NGS data analysis
• Knowledge of sequence liabilities and developability assessment
• Proficiency in interpreting data from the following assays: flow cytometry, analytical SEC, LCMS, HIC, SPR, and BLI

Compensation:

In addition to a competitive compensation package with stock options, the company also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance.

Job Type:

Full-time

$115,000-145,000

Supplemental Pay Types:

• 401(k)
• Employee assistance program
• Flexible spending account
• Health insurance
• Life insurance
• Paid time off
• Parental leave
• Relocation assistance
• Vision insurance

Seniority level

• Seniority levelMid-Senior level

Employment type

• Employment typeFull-time

Job function

• Job functionResearch, Analyst, and Information Technology

Referrals increase your chances of interviewing at Work In Biotech by 2x

Get notified about new Associate Scientist jobs in San Diego, CA.

Production Chemist I(Potential to adapt to an ISO, GMP, or GLP environment)

San Diego Metropolitan Area $150,000 - $170,000 4 days ago

Scientist I, Immunoassay Manufacturing and DevelopmentScientist I, Immunoassay Manufacturing and DevelopmentQuality Control Chemist I - BS Degree in Chemistry (Entry Level & Required QC Exp)

We're unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

#J-18808-Ljbffr