Development of Chemical Sensors through Peptide Interactions
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Development of Chemical Sensors through Peptide Interactions

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Development of Chemical Sensors through Peptide Interactions

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Description

A research opportunity is available in the Biomaterials & Assembly Branch at DEVCOM Army Research Laboratory (ARL) in Adelphi, MD. A post-baccalaureate opportunity is available for the development, synthesis, & characterization of peptide-based receptors for detecting chemical/biological targets of interest. This work supports the Defense Threat Reduction Agency's R&D efforts in colorimetric detection technologies for sensing chemical threats. Work is expected to include the chemical synthesis and assessment of affinity kinetics exhibited by peptide receptors derived from One-Bead-One-Compound (OBOC) peptide library screens against protein targets of interest. Backgrounds in Chemistry, Biochemistry & biochemical engineering and related disciplines are preferred.

Key Responsibilities:

Chemically Synthesize & purify peptide-based receptors by Solid Phase Peptide Synthesis (SPPS)

Characterize peptide – target binding by high-throughput and kinetic assays

Conduct screening of OBOC libraries against targets of interest

Support & Develop receptor integration strategies into various sensing platforms

Write technical reports for internal publication

Work on a multi-disciplinary team and contribute to publications/patents

Organization

DEVCOM Army Research Laboratory

Reference Code

ARL-R-BBS-400010-F1

Description

A research opportunity is available in the Biomaterials & Assembly Branch at DEVCOM Army Research Laboratory (ARL) in Adelphi, MD. A post-baccalaureate opportunity is available for the development, synthesis, & characterization of peptide-based receptors for detecting chemical/biological targets of interest. This work supports the Defense Threat Reduction Agency's R&D efforts in colorimetric detection technologies for sensing chemical threats. Work is expected to include the chemical synthesis and assessment of affinity kinetics exhibited by peptide receptors derived from One-Bead-One-Compound (OBOC) peptide library screens against protein targets of interest. Backgrounds in Chemistry, Biochemistry & biochemical engineering and related disciplines are preferred.

Key Responsibilities:

Chemically Synthesize & purify peptide-based receptors by Solid Phase Peptide Synthesis (SPPS)

Characterize peptide – target binding by high-throughput and kinetic assays

Conduct screening of OBOC libraries against targets of interest

Support & Develop receptor integration strategies into various sensing platforms

Write technical reports for internal publication

Work on a multi-disciplinary team and contribute to publications/patents

Advisor Name: Alexander Winton

Advisor Email: ...@army.mil

About ARD

ARL's Army Research Directorate (ARD) focuses on exploiting concept development, discovery, technology development, and transition of the most promising disruptive science and technology to deliver to the Army fundamentally advantageous science-based capabilities through laboratory's 11 research competencies. This intramural research directorate also manages the laboratory's essential research programs, which are flagship research efforts focused on delivering defined outcomes.

About ARL-RAP

The Army Research Laboratory Research Associateship Program (ARL-RAP) is designed to significantly increase the involvement of creative and highly trained scientists and engineers from academia and industry in scientific and technical areas of interest and relevance to the Army. Scientists and Engineers at the CCDC Army Research Laboratory (ARL) help shape and execute the Army's program for meeting the challenge of developing technologies that will support Army forces in meeting future operational needs by pursuing scientific research and technological developments in diverse fields such as: applied mathematics, atmospheric characterization, simulation and human modeling, digital/optical signal processing, nanotechnology, material science and technology, multifunctional technology, combustion processes, propulsion and flight physics, communication and networking, and computational and information sciences.

About BIOLOGICAL AND BIOTECHNOLOGY SCIENCES (BBS)

Biological related disciplines, including synthetic biology, biological materials, biological/abiological interfaces, and biological effect.

A complete application includes:

Curriculum Vitae or Resume

Three References Forms

• An email with a link to the reference form will be available in Zintellect to the applicant upon completion of the on-line application. Please send this email to persons you have selected to complete a reference.
• References should be from persons familiar with your educational and professional qualifications (include your thesis or dissertation advisor, if applicable)

Transcripts

• Transcript verifying receipt of degree must be submitted with the application. Student/unofficial copy is acceptable

If selected by an advisor the participant will also be required to write a research proposal to submit to the ARL-RAP review panel for:

• Research topic should relate to a specific opportunity at ARL (see Research Areas)
• The objective of the research topic should be clear and have a defined outcome
• Explain the direction you plan to pursue
• Include expected period for completing the study
• Include a brief background such as preparation and motivation for the research
• References of published efforts may be used to improve the proposal

A link to upload the proposal will be provided once the advisor has made their selection.

Questions about this opportunity? Please email ...@orau.org.

Point of Contact

ARL

Eligibility Requirements

12)

• Citizenship: U.S. Citizen Only
• Degree: Bachelor's Degree, Master's Degree, or Doctoral Degree.
• Academic Level(s): Any academic level.
• Discipline(s):
• Chemistry and Materials Sciences
• Analytical Chemistry
• Bio-inorganic Chemistry
• Bio-organic Chemistry
• Biophysical Chemistry
• Chemistry (General)
• Environmental Chemistry
• Inorganic Chemistry
• Materials Sciences
• Organic Chemistry
• Physical Chemistry
• Polymer Chemistry
• Theoretical Chemistry

Seniority level

• Internship

Employment type

• Full-time

Job function

• Other

Industries

• Government Administration

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